The No BS Guide to Probiotics for Your Brain (2022)

The No BS Guide to Probiotics for Your Brain (1)Share on Pinterest

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.

Yep, your gut talks to your brain

You know that fluttering feeling in your stomach before you give a toast? Or the sudden loss of appetite that comes with upsetting news? That’s your brain communicating with your gut’s microbiota, or more scientifically known as the gut-brain axis.

And it goes both ways. Your gut’s microbiota can also talk to your brain. In fact, recent studies show that consuming probiotics may help improve your mood and smarts.

“I can foresee more widespread usage of probiotics in the treatment of mental health, especially since most people can tolerate them well,” says Aparna Iyer, MD, assistant professor of psychiatry at the University of Texas Southwestern Medical Center.

Iyer says more research is needed to help determine what strains or doses of probiotics might be the most therapeutic, but in the meantime, you can still give your brain a boost by adding probiotics — the smart way — to your diet.

You might think your stomach has a mind of its own sometimes, and you’re right. The gut houses our second brain, the enteric nervous system (ENS), and it’s our job to give the second brain the impression that everything’s hunky-dory down there so that it gabs the good news to brain number one.

Share on Pinterest

“The healthy functioning of one is conducive to healthy functioning of the other,” Iyer says. That’s a prime reason to get geeky about good bacteria consumption, but it’s not just about eating kefir and sauerkraut.

There are specific probiotic strains with more research than others, specifically the Lactobacillus and Bifidobacterium strains (specifically the L. helveticus and B. longum strains). Researchers are even calling these strains “psychobiotics” for their potential therapeutic benefits. But here’s what science really knows about probiotics and the brain-gut connection:

Probiotic strainWhat science says
B. longummay reduce depression and anxiety, helps people with IBS
B. bifidumhelps generate vitamins such as K and B-12, which may also influence mood
B. infantisincreased relaxation in rats and helped with treating irritable bowel syndrome
L. reuteriknown to have an anti-pain effect in mice and can help increase excitability
L. plantarumsignificantly increased serotonin and dopamine in mice and reduced anxious behavior when they were in a maze
L. acidophilusmay help reduce cholesterol and supports nutrient absorption
L. helveticusrats administered with L. helveticus showed a decline in anxiety scores but another 2017 study found no difference

Try all probiotic foods: Food products often have a mix of probiotics — and not just one type (although you can purchase a specific strain in pill form).

For example, one study, published in the Frontiers of Neuroscience, showed that people with Alzheimer’s disease who took probiotics (a mixture of L. acidophilus, L. casei, B. bifidum,and L. fermentum) experienced positive effects on cognitive functions like learning power and memory.

Research is ongoing with the brain-gut connection and how probiotics can help. But so far, the work is promising — and, of course, you don’t have to have a chronic illness to reap the potential brain-boosting benefits.

(Video) Do This Before You Take A Probiotic - Probiotic Benefits

(Video) A No BS Guide To Supplements

With her clients, Iyer prefers the food, rather than pill, approach. “We find ways of incorporating this aspect of their diet into an overall healthy lifestyle,” she says. “And the patient then ultimately has the control of how to make this change in a way that fits into his or her dietary preferences.”

Probiotics are most common in fermented foods. That means you can easily incorporate them just by getting creative with your meals.

Add a side of probiotics, such as:Common probiotic strains
sauerkraut to pizza L. plantarum, B. bifidum
kimchi to noodle or rice dishesL. plantarum
Greek yogurt in place of sour cream B. infantis, B. bifidum, or lactobacillus
kefir to a smoothieB. infantis, B. bifidum, or lactobacillus
extra pickles to your sandwich or burgerL. plantarum
kombucha with a meallactobacillus

Every person’s microbiome is different, so don’t eat them all at once. When you start to add these foods to your diet, take it slow. For example, you might try a half cup of kefir first and see how your body reacts before working your way up to a full serving, which is one cup.

Experiencing gas, bloating, and increased bowel activity isn’t uncommon. If you don’t experience abdominal discomfort, experiment with more foods until you naturally incorporate probiotics throughout the day.

Eating probiotics with intention has the added benefit of a built-in lifestyle change. “Generally, when my clients introduce probiotics into their diet, they are taking their health seriously and also eating healthy as well,” says Natalie Rizzo, MS, RD, based in New York City. “Both of those things together can definitely lead to health improvements.”

Rizzo recognizes that getting a good dose of probiotic foods every day might be a challenge for some people. Always try to get probiotics naturally first. If you’re unable to get in enough, Rizzo suggests a probiotic pill. You can find them at health food stores.

(Video) Probiotics For Gut Health Warning Signs That You Need Probiotics

Iyer recommends checking with your physician about dosage and to find a trusted, reputable manufacturer. Probiotics and other supplements aren’t monitored by the U.S. Food and Drug Administration (FDA). There could be concerns about safety, quality, or even packaging.

What’s the deal with supplements?

Probiotic supplements typically contain a combination of several bacteria species. The recommended daily dosage ranges from 1 billion to 10 billion colony forming units (CFUs). Supplements also often contain a mixture of probiotics strains, but the brands will often list which strains they contain.

Probiotic productProbiotic strains
Mood Boosting Probiotic ($23.88)B. infantis, B. longum
Swanson L. Reuteri Plus with L. Rhamnosus, L. Acidophilus ($11.54)L. Reuteri, L. Rhamnosus, L. Acidophilus
Garden of Life Probiotic and Mood Supplement ($31.25)L. helveticus R0052, B. longum R0175
100 Naturals Upbiotics ($17.53)L. acidophilus, L. rhamnosus, L. plantarum, L. Caise, B. longum, B. breve, B. subtilis

Start with a dose of lower CFUs and see how your body reacts before working your way up to a full dose.

Tess Catlett started taking a daily probiotic to help relieve bloating. Only she started at a high dose (10 billion CFUs) and found herself in abdominal distress.

“After two or three days of taking it, I began to experience the worst stomachache I’ve had in years,” she says. “Picture the pain of menstrual cramps and the nausea of food poisoning all wrapped up in one.”

But thankfully after adjusting her dose and taking the probiotic continuously for two weeks, Catlett noticed a clear difference in the bloating.

The best time to take a probiotic is with food. A 2011 study found that taking a probiotic pill with a meal or 30 minutes before a meal (but not 30 minutes after) is the optimal way to keep all the benefits of probiotic supplements.

For people who have trouble remembering to take a pill, Rizzo suggests associating your intake with a certain daily activity. You could get in the habit of taking the supplement when you brush your teeth right after you eat breakfast, for example.

Share on Pinterest

Keep in mind that it may take a few weeks for the brain benefits to kick in.

“Even though this might seem like a long time, the reality is that most antidepressants also take this long, too,” Iyer says. “Most of my patients will first report feeling physically better, with less stomach discomfort and less bloating. Shortly thereafter, they will often also start feeling lower levels of anxiety and improvement of their mood,” she adds.

Have finals approaching? Stressed with impending work deadlines? Concerned about seasonal affective disorder (SAD)? Maybe your mood plummets in the days leading up to your period. Or maybe you’re going through a breakup or you’re just having a rough go of it lately. These are all times when getting super smart and intentional with your diet and probiotic intake can make all the difference.

Probiotics and gut health are intimately linked to immune function, which is your body’s ability to fight infection or disease. Incorporating probiotics regularly is your best bet for continued well-being. But don’t be afraid to ramp up your intake a little more when you anticipate you’ll need more help.

This information isn’t intended to encourage anyone to stop taking their medications. Don’t stop taking antidepressants or other prescriptions without first consulting with your healthcare professional and getting the go ahead along with a plan for slowly and properly weaning off.

5 Things You Might Not Know About the Gut-Brain Connection

(Video) Probiotic Benefits | Top Signs You Should Be Taking A Probiotics

Jennifer Chesak is a Nashville-based freelance book editor and writing instructor. She’s also an adventure travel, fitness, and health writer for several national publications. She earned her Master of Science in journalism from Northwestern’s Medill and is working on her first fiction novel, set in her native state of North Dakota.


What probiotic does Chris Kresser recommend? ›

's Daily Synbiotic is the most effective, well-tolerated, & evidence-based probiotic that I've encountered in over a decade of clinical practice. My entire family uses it, and I recommend it to almost all of my patients.

Do probiotics help with brain function? ›

Probiotics can do more than improve your gut health. They also may indirectly enhance your brain, too. Research shows that the gut and brain are connected, a partnership called the gut-brain axis.

What are the best probiotics for brain health? ›

Bifidobacterium Longum (found in sauerkraut and pickles) and lactobacillus brevis have been shown to improve levels of BDNF (brain derived neurotrophic factor) which protects and promotes brain cell growth. Bifidobacterium lactic (fermented milk products like kefir) has been shown to improve immunity.

What probiotic does Dave Asprey recommend? ›

Omni-Biotic Stress Release probiotic is recommended by Dave Asprey as the ultimate stress management upgrade on “The Human Upgrade Podcast.” A balanced gut microbiome (the world of billions of bacteria in our intestines) is essential for health and longevity.

Can I take cinnamon with probiotics? ›

Conclusions: According to the current results, the use of probiotic supplements (individually or in combination with cinnamon) leads to a reduction in blood glucose and an increase in antioxidant enzymes in people with type 2 diabetes.

When should I take my probiotic? ›

Probiotics are most effective when taken on an empty stomach. Taking probiotics at least 30 minutes before a meal will reduce the time it takes for the good bacteria to get to your gut. Probiotics are dietary supplements containing beneficial bacteria naturally occurring in your intestinal tract.

Do probiotics improve memory? ›

Probiotics Benefit Brain Function

In a recent study, participants took probiotics for four weeks and a placebo for four weeks. They scored higher on memory tests and reported less anxiety and stress while taking probiotics than when taking placebo.

Do probiotics help dementia? ›

Probiotics are known to be one of the best preventative measures against cognitive decline in AD. Numerous in vivo trials and recent clinical trials have proven the effectiveness of selected bacterial strains in slowing down the progression of AD.

Do probiotics help brain fog? ›

Acidosis & Brain Fog

Elimination of the probiotics–along with the antibiotic therapies–led to a significant improvement of symptoms in 70% of study participants, and a complete resolution of brain fogginess in 85%.

Do probiotics help with brain inflammation? ›

Probiotics Improve Inflammation-Associated Sickness Behavior by Altering Communication between the Peripheral Immune System and the Brain.

How long does it take for probiotics to help anxiety? ›

Some probiotics have been shown to improve symptoms of stress, anxiety and depression ( 25 , 26 ). One small study of people with irritable bowel syndrome and mild-to-moderate anxiety or depression found that taking a probiotic called Bifidobacterium longum NCC3001 for six weeks significantly improved symptoms ( 27 ).

Can probiotics help nerve damage? ›

As living bacteria, probiotics can help improve digestion, enhance immunity, and alleviate pain associated with intestinal dysfunction. They may also inhibit immune signaling transmission associated with neuropathic pain.

Does gut bacteria affect brain function? ›

Gut bacteria also produce hundreds of neurochemicals that the brain uses to regulate basic physiological processes as well as mental processes such as learning, memory and mood. For example, gut bacteria manufacture about 95 percent of the body's supply of serotonin, which influences both mood and GI activity.

What happens to your body when you start taking probiotics? ›

Probiotics are the good bacteria in the gut which help support a healthy gut microbiome. Some positive effects of probiotics include fighting off bad bacteria, improving digestion and regulating bowel movements, supporting the immune system, and helping with weight loss.

Does the gut affect the brain? ›

A troubled intestine can send signals to the brain, just as a troubled brain can send signals to the gut. Therefore, a person's stomach or intestinal distress can be the cause or the product of anxiety, stress, or depression. That's because the brain and the gastrointestinal (GI) system are intimately connected.

What are the signs that probiotics are working? ›

But there are some common indicators that they may be working for you.
  • Less stomach pain. For some people, certain probiotics can help with stomach pain and cramps. ...
  • More frequent poops. ...
  • Less bloating. ...
  • Improved sleep. ...
  • Better mood, memory, and mental clarity. ...
  • Fewer vaginal infections.
20 Jul 2022


1. Change Your Brain: The Power Of Neuroplasticity And Braincare - Dr Tara Swart
(Deep Dive with Ali Abdaal )
2. Health Benefits of Postbiotics - Your Gut Needs These!
(Dr. Nick Zyrowski)
3. Is Gluten Really THAT Bad? Real Doctor Reveals the Truth
(Dr. Michael Ruscio, DNM, DC)
4. The Gut And The Brain Connection - An Expert Explains
(Ryan Mitchel Brown)
5. Probiotics for Gut Health + Why Most Probiotic Foods & Supplements Don’t Work!
(Essential Stacks)
6. Anxiety Nutrition Tips (3 Easy Tips)
(Kelsey Ale, Nutritional Therapist)

Top Articles

Latest Posts

Article information

Author: Manual Maggio

Last Updated: 11/24/2022

Views: 5535

Rating: 4.9 / 5 (49 voted)

Reviews: 88% of readers found this page helpful

Author information

Name: Manual Maggio

Birthday: 1998-01-20

Address: 359 Kelvin Stream, Lake Eldonview, MT 33517-1242

Phone: +577037762465

Job: Product Hospitality Supervisor

Hobby: Gardening, Web surfing, Video gaming, Amateur radio, Flag Football, Reading, Table tennis

Introduction: My name is Manual Maggio, I am a thankful, tender, adventurous, delightful, fantastic, proud, graceful person who loves writing and wants to share my knowledge and understanding with you.